Computational Methods for Protein Structure Prediction and Modeling: Volume 1: Basic Characterization (Biological and Medical Physics, Biomedical Engineering)

Volume certainly one of this two-volume series specializes in the fundamental characterization of identified protein constructions, and constitution prediction from protein series info. 11 chapters survey of the sector, overlaying key issues in modeling, strength fields, class, computational equipment, and constitution prediction. every one bankruptcy is a self contained overview protecting definition of the matter and ancient point of view; mathematical formula; computational tools and algorithms; functionality effects; current software program; strengths, pitfalls, demanding situations, and destiny research.

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Sci. united states 89:2195–2199. Kelley, L. A. , MacCallum, R. M. , and Sternberg, M. J. E. 2000. more suitable genome annotation utilizing structural profiles within the application 3D-PSSM. J. Mol. Biol. 299:501–522. SVNY330-Xu-Vol-I November 2, 2006 16:58 1. A old point of view and review 37 Kihara, D. , Lu, H. , Kolinski, A. , and Skolnick, J. 2001. TOUCHSTONE: An ab initio protein constitution prediction strategy that makes use of threading-based tertiary restraints. Proc. Natl. Acad. Sci. united states 98:10125–10130. Kim, D. E. , Chivian, D. , and Baker, D. 2004. Protein constitution prediction and research utilizing the Robetta server. Nucleic Acids Res. 32(Suppl. 2):W526–531. Klein, P. , Kanehisa, M. , and DeLisi, C. 1985. The detection and category of membrane-spanning proteins. Biochim. Biophys. Acta Prot. Struct. Mol. Enzymol. 815:468–476. Koehl, P. , and Delarue, M. 1995. A self constant suggest box method of simultaneous hole closure and side-chain positioning in homology modelling. Nat. Struct. Biol. 2:163–170. Koh, I. Y. Y. , Eyrich, V. A. , Marti-Renom, M. A. , Przybylski, D. , Madhusudhan, M. S. , Eswar, N. , Grana, O. , Pazos, F. , Valencia, A. , Sali, A. , and Rost, B. 2003. EVA: review of protein constitution prediction servers. Nucleic Acids Res. 31:3311–3315. Kolinski, A. , and Skolnick, J. 1994a. Monte Carlo simulation of protein folding. II. program to protein A, ROP, and crambin. Proteins 18:353–366. Kolinski, A. , and Skolnick, J. 1994b. Monte Carlo simulations of protein folding. I. Lattice version and interplay scheme. Proteins 18:338–352. Kolinski, A. , and Skolnick, J. 1998. meeting of protein constitution from sparse experimental info: an effective Monte Carlo version. Proteins 32:475–494. Kolinski, A. , and Skolnick, J. 2004. lowered types of proteins and their purposes. Polymer 45:511–524. Kosinski, J. , Cymerman, I. A. , Feder, M. , Kurowski, M. A. , Sasin, J. M. , and Bujnicki, J. M. 2003. A “FRankenstein’s monster” method of comparative modeling: Merging the best fragments of Fold-Recognition versions and iterative version refinement aided by means of 3D constitution assessment. Proteins 53(S6):369–379. Kriventseva, E. V. , Koch, I. , Apweiler, R. , Vingron, M. , Bork, P. , Gelfand, M. S. , and Sunyaev, S. 2003. elevate of sensible range by means of substitute splicing. traits Genet. 19:124–128. Krogh, A. , Brown, M. , Mian, I. S. , Sjolander, okay. , and Haussler, D. 1994. Hidden Markov versions in computational biology: purposes to protein modeling. J. Mol. Biol. 235:1501–1531. Krogh, A. , Larsson, B. , von Heijne, G. , and Sonnhammer, E. L. L. 2001. Predicting transmembrane protein topology with a hidden Markov version: program to accomplish genomes. J. Mol. Biol. 305:567–580. Kurowski, M. A. , and Bujnicki, J. M. 2003. GeneSilico protein constitution prediction meta-server. Nucleic Acids Res. 31:3305–3307. Kyte, J. , and Doolittle, R. F. 1982. an easy approach for exhibiting the hydropathic personality of a protein. J. Mol. Biol. 157:105–132. Lau, ok. F. , and Dill, ok. A. 1989. A lattice statistical mechanics version of the conformational and series areas of proteins. Macromolecules 22:3986–3997. Lee, C. 1994. Predicting protein mutant energetics by way of self-consistent ensemble optimization.

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